Core Facilities

Bioinformatics Core
Gonda 5558
Dr. Eric Sobel
Department of Human Genetics 310-825-1111

The Bioinformatics Core maintains state-of-the-art computing resources for genetic studies: software library, computational cluster, storage array (replicated off-site), and public & private, web & database servers.

Informatics Center for Neurogenetics and Neurogenomics
Gonda 1346
Dr. Nam Tran

Informatics Center for Neurogenetics and Neurogenomics provides advanced analysis and informatics support to neuroscientists at UCLA, including GGNRC residents.

UCLA Neurosciences Genomics Core (UNGC)
Gonda 3554
Joseph DeYoung

The UCLA Neurosciences Genomics Core (UNGC) is currently operating an Illumina BeadLab 1000 high throughput SNP genotyping system (iScan), a Sequenom MassArray Compact mass spec and and two Illumina HiSeq 2500 next generation sequencing instruments in the Gonda research facility on the UCLA campus. The UNGC is a not for profit academic resource available to researchers in the Southern California region and beyond. Directed by Dr. Nelson Freimer, the UNGC is committed to providing equivalent access to its members at all institutions.
Services include: DNA sequencing (Whole genome, RNASeq/whole transcriptome, snp discovery etc.); Custom snp genotyping using the high throughput Illumina GoldenGate and iSelect assays and with the Sequenom iPlex assay; Genotyping using all currently available Illumina Infinium whole genome chips; Gene expression using all currently available expression chips for human and mouse; Whole genome methylation using Illumina Meth-450 chips.

Carol Moss Spivak Cell Imaging Core (within the California Nanosystems Institute)
CNSI Building B145
Dr. Matthew Schibler

The Carol Moss Spivak Imaging Facility is now part of the Advanced Light Microscopy/Spectroscopy (ALMS) Technology Center and the Leica Center of Excellence at the California NanoSystems Institute (CNSI) at UCLA. The ALMS Laboratories are located in the CNSI building, where two optical suites house light microscopes and small animal imagers with the required environment control (low vibration, air-filtered, air-conditioned to 1ºC and light-tight) and services. The ALMS Laboratories currently provide wide-field fluorescence microscopy, stereo microscopy, confocal one-photon and two-photon laser scanning confocal microscopy, lightsheet microscopy, spinning disk ultra-fast confocal microscopy, Total Internal Reflection Fluorescence (TIRF) microscopy Fluorescence Resonance Energy Transfer (FRET), Fluorescence Lifetime Imaging (FLIM), Fluorescence Correlation Spectroscopy (FCS), time-correlated-single-photon-counting (TCSPC), near-infrared (NIR) imaging, super-resolution Stimulated Emission Depletion (STED) confocal microscopy and Stochastic Optical Reconstruction Microscopy (STORM), macroscopic small animal spectral imaging and laser capture microdissection.

For more information, please visit the ALMS website at: http://alms.cnsi.ucla.edu.
To become an ALMS User, please contact: alms@cnsi.ucla.edu.
Reservations for ALMS equipment may be made here.