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Core Facilities

Bioinformatics Core
Gonda 5558
Dr. Eric Sobel
Department of Human Genetics 310-825-1111
esobel@mednet.ucla.edu

The Bioinformatics Core maintains state-of-the-art computing resources for genetic studies: software library, computational cluster, storage array (replicated off-site), and public & private, web & database servers.

Genotyping and DNA Sequencing Core
CHS 36-125
Dr. Jeanette Papp
Department of Human Genetics 310-825-6204
jcpapp@ucla.edu

Sequencing & Genotyping Core Facility provides sequencing and genotyping services to the research genetics community. A wide variety of genetic technologies are available which can accommodate studies ranging from large-scale, high-throughput projects, to small-scale, customized projects.

DNA Microarray Core
Gonda 5554
Dr. Stanley Nelson
Traci Toy
Departments of Pediatrics & Human Genetics 310-267-1947
microarray@mednet.ucla.edu

DNA Microarray Core Facility provides user access to DNA microarray and next generation sequencing technologies in order to permit individual labs to have access to broad-based genome-scale analytical tools.

Informatics Center for Neurogenetics and Neurogenomics
Gonda 1346
Dr. Nam Tran
310-983-1454
nam.tran@ucla.edu

Informatics Center for Neurogenetics and Neurogenomics provides advanced analysis and informatics support to neuroscientists at UCLA, including GGNRC residents.

UCLA Neurosciences Genomics Core (UNGC)
Gonda 3554
Joseph DeYoung
310-825-2390
jdeyoung@mednet.ucla.edu

The UCLA Neurosciences Genomics Core (UNGC) is currently operating an Illumina BeadLab 1000 high throughput SNP genotyping system (iScan), a Sequenom MassArray Compact mass spec and and two Illumina HiSeq 2500 next generation sequencing instruments in the Gonda research facility on the UCLA campus. The UNGC is a not for profit academic resource available to researchers in the Southern California region and beyond. Directed by Dr. Nelson Freimer, the UNGC is committed to providing equivalent access to its members at all institutions.
Services include: DNA sequencing (Whole genome, RNASeq/whole transcriptome, snp discovery etc.); Custom snp genotyping using the high throughput Illumina GoldenGate and iSelect assays and with the Sequenom iPlex assay; Genotyping using all currently available Illumina Infinium whole genome chips; Gene expression using all currently available expression chips for human and mouse; Whole genome methylation using Illumina Meth-450 chips.

Carol Moss Spivak Cell Imaging Core (within the California Nanosystems Institute)
CNSI Building B145
Dr. Matthew Schibler
310-983-1077
mschibler@mednet.ucla.edu

The Advanced Light Microscopy/Spectroscopy Shared Facility (of which the Carol Moss Spivak Imaging Facility is now a part) in the CNSI provides a collection of high-level, customized biological fluorescence microscopes and small-animal imaging devices that provide the ability to study biological processes with high spatial and temporal resolution in whole organisms and in living cells down to the single molecule detection level with nanometer-accuracy. The facility currently has the following technologies: Wide-field Fluorescence Imaging Microscopy, Confocal One-Photon and Two-Photon Laser Scanning Microscopy, (both point scanning and spinning disk), Fluorescence Correlation Spectroscopy (FCS), Fluorescence Resonance Energy Transfer (FRET), microscopic and macroscopic Fluorescence Lifetime Imaging (FLIM) with Time-Correlated-Single-Photon-Counting (TCSPC) and Near-Infrared (NIR) Detection, Stimulated Emission Depletion laser-scanning microscopy (STED) (a super-resolution technique), both microscopic and macroscopic (small animal) Spectral Unmixing and Laser Microdissection.